The Omics Of Rhinoviruses

The human rhinoviruses comprise three species, RV-A, RV-B and RV-C, in the Enterovirus genus of Picornaviridae. Prior to the current 'Omics Era' viruses were typically binned by dominant disease phenotypes after a simple parsing of their RNA or DNA genotypes. But as the 'omics' has piled up, and more and more sequences have emerged, the similarities in genome organization, receptor use, aetiology and structures has become ever more apparent. This chapter summarizes key aspects of RV taxonomy and the physical and biochemical parameters by which these viruses are currently studied.