Macrophages/Microvesicles And Their Task In Viral Diseases

DYNAMICS OF IMMUNE ACTIVATION IN VIRAL DISEASES(2020)

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摘要
Viral infectious diseases are mainly associated with immunological responses triggered by immunocytes present in the circulation like macrophages. A better understanding of these immunity mechanisms will help us to control the progression of the disease to chronic conditions. Microvesicles are an extracellular group of plasma membrane secretions, which play a significant role in the spread of infection or evasion of viral entities to surrounding healthy cells acting as a viral vehicle. Their involvement in the viral cycle can be utilized productively in hampering the period by developing the antibodies that shield the evasion. These extracellular vesicles will facilitate the communication between the cells in the body humoral environment leading to host and viral interactions in the immune system. Thereby attempting to study the role of macrophages in the immunity process will help us to eliminate the viral pathogens by either delaying or damaging their spread to healthy cells. Focusing on these mechanisms of the microvesicles and macrophages will help lead to the early cure of many life-threatening infectious diseases like HIV, Hepatitis, and Dengue by developing a single specific antibiotic.
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关键词
Macrophages, Viral cycle, HIV, Hepatitis, Dengue, Humoral environment, Extracellular vesicles
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