Translational Neuroelectronics

Neuroelectronic devices are critical for the diagnosis and treatment of neuropsychiatric conditions, and are hypothesized to have many more applications. A wide variety of materials and approaches have been utilized to create innovative neuroelectronic device components, from the tissue interface and acquisition electronics to interconnects and encapsulation. Although traditional materials have a strong track record of stability and safety within a narrow range of use, many of their properties are suboptimal for chronic implantation in body tissue. Material advances harnessed to form all the components required for fully integrated neuroelectronic devices hold promise for improving the long-term efficacy and biocompatibility of these devices within physiological environments. Here, it is aimed to provide a comprehensive overview of materials and devices used in translational neuroelectronics, from acquisition and stimulation interfaces to methods for power delivery and real time processing of neural signals.