An Efficient Two-Step Synthesis Of Novel Substituted Pyrazolo[1,5-A]-[1,3,5]-Triazines And Pyrazolo[1,5-A]-[1,3,5] Triazinones

The synthesis of a series of pyrazolotriazine derivatives is described in two steps. The reaction of hydrazine with substituted thioamides leads to the formation of 3,5-diaminopyrazoles. The latter reacts with the N-acyl imidates and the N-ethoxy imidate yielding the corresponding substituted pyrazolotriazines and pyrazolotriazinones. The structure of all these compounds has been confirmed by IR, (HNMR)-H-1, (CNMR)-C-13 and elemental analysis.