Synthesis And C-Alkylation Of C-Protected Beta-Enamino Acid Derivatives From Oxa- Thia- And Imidazolines

S Fustero, Md Diaz,A Asensio,A Navarro, Js Kong, E Aguilar

TETRAHEDRON（1999）

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摘要

Various heterocycles 3a-h can be readily metallated and condensed with a variety of organic nitriles to afford C-protected beta-enamino acid derivatives 1 (or 2). Procedures for alkylation of compounds 1 to obtain 2 as well as a "one-pot" preparation of 2 from 3 are also described. (C) 1999 Elsevier Science Ltd. All rights reserved.

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关键词

oxazolines, thiazolines, enamines, alkylation, theoretical studies

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