Severity Classification For Sickle Cell Disease: A Rand/Ucla Modified Delphi Panel

Background: The clinical course of sickle cell disease (SCD) varies greatly by patient depending on age, complications, comorbidities, and psychosocial health. While researchers have developed models to predict complications and mortality, there is currently no accepted classification system of overall SCD severity. Our goal was to develop a severity classification system that could be tested for its ability to predict clinical outcomes.