Green Approach On Achieving Zinc Oxide Nanoparticles And Its Potential Bactericidal As Well As Antioxidant Activity

INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH(2020)

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摘要
Biosynthesis of nanoparticles by biological means especially plant extract plays a major role in the field of nanotechnology. In the present study, the aqueous extract of lemon peel (Citrus limon) was used for the green synthesis of ZnO nanoparticles using 0.1 M Zn(NO3)(2) as a precursor in alkaline condition using NaOH with vigorous stirr ing for 3 h. ZnO NPs obtained were characterized by UV-vis spectroscopy in which the surface Plasmon resonance was 310 nm, followed by XRD, FTIR that showed appropriate speaks for various chemical groups present including ZnO NPs and AFM results shows monodispersed in nature. Further, the antibacterial property of ZnO NPs synthesized by the green method was revalued by the well diffusion method. The zone of inhibition was found to be 9 mm for 100 mu L and 7 mm for 100 mu L for respective strains Klebsiella aerogene and Serratia marcescen. Significant antioxidant activity was exhibited by NPs through scavenging of 1, 1-Diphenyl-2-picrylhydrazyl (DPPH) free radicals. Thus, the use of aqueous peel extract as a capping agent would improve the antibacterial property of ZnO nanoparticle and can be developed as antibacterial agents against a wide range of microorganisms to control and prevent the spreading and persistence of bacterial infections. Followed by Edax and Zeta was also included.
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关键词
Zinc oxide nanoparticles, Lemon peel, Antioxidant, Antibacterial, Green approach
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