Crystallization control via membrane distillation-crystallization: A review

Membrane distillation-crystallization is a promising method potentially able to outperform the conventional crystallization processes in terms of crystallization control and product quality. This review gives a comprehensive overview of the current research addressing membrane distillation-crystallization and its advantages for crystallization control. More specifically, this work focuses on the impact of different parameters on crystal morphology and quality. The research papers about membrane distillation-crystallization reporting control of crystal habit, polymorphism, crystal size distribution, coefficient of variation, crystal yield, crystal purity, nucleation rate, growth rate and induction time are comprehensively reviewed and discussed. The methods and instruments of measure are systematically specified, and common guidelines are proposed to adjust discrepancies. Finally, the review indulges in a critical assessment of the challenges faced by membrane distillation-crystallization.