Retzius-Sparing (Rsrarp) Vs. Conventional Robotic Assisted Radical Prostatectomy (Crarp)-A Prospective, Randomised, Single Blinded Trial-Results Of Early Continence

You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy I (MP15)1 Sep 2021MP15-14 RETZIUS-SPARING (rsRARP) vs. CONVENTIONAL ROBOTIC ASSISTED RADICAL PROSTATECTOMY (cRARP)—A PROSPECTIVE, RANDOMISED, SINGLE BLINDED TRIAL—RESULTS OF EARLY CONTINENCE Joanne Nyarangi-Dix, Viktoria Schuetz, Maximilian Guettlein, David Wuerkner, Luisa Hofer, Magdalena Goertz, Philipp Reimold, Katrin Kaltenecker, Svenja Dieffenbacher, Georgi Tosev, and Markus Hohenfellner Joanne Nyarangi-DixJoanne Nyarangi-Dix More articles by this author , Viktoria SchuetzViktoria Schuetz More articles by this author , Maximilian GuettleinMaximilian Guettlein More articles by this author , David WuerknerDavid Wuerkner More articles by this author , Luisa HoferLuisa Hofer More articles by this author , Magdalena GoertzMagdalena Goertz More articles by this author , Philipp ReimoldPhilipp Reimold More articles by this author , Katrin KalteneckerKatrin Kaltenecker More articles by this author , Svenja DieffenbacherSvenja Dieffenbacher More articles by this author , Georgi TosevGeorgi Tosev More articles by this author , and Markus HohenfellnerMarkus Hohenfellner More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001996.14AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Since the introduction of rsRARP in 2010 three prospective RCTs comparing rsRARP and cRARP have been published. To further evaluate the results published until now we conducted a prospective, randomised, single blinded trial. METHODS: A total of 202 men (age 64.2±6.9 yrs.) with localised prostate cancer (PCa) were included and randomised 1:1. Pre-operative as well as one, four and twelve weeks after foley catheter removal functional parameters (continence, sexual function) were registered via validated questionnaires (ICIQ-UI SF, IPSS, IIEF-5, QoL). RESULTS: Three months postoperative complete data sets were available for 186 patients (cRARP n=92, rsRARP n=94). Pre-operative characteristics were well balanced between the two groups. Hospital stay (4.1±0.9 vs. 5.4±5.8 d; p=0.037) and console time for prostate dissection (36.8±8.8 vs. 46.8±12.8Min; p=0.017) were significantly shorter in the rsRARP-Group. Also did patients after rsRARP have a faster recovery of continence (after 1 week p=0.003, 3 months p=0.022), lower number of incontinence pads used per day (p=0.001, 0.011, 0.019 after 1, 4 and 12 weeks respectively) and a lower impairment in quality of life caused by involuntary loss of urine (p=0.001, 0.002, 0.005, 1, 4 and 12 weeks respectively). Oncological follow-up data is not yet available for this cohort. From our experience the rate of BCR after rsRARP is 5.9% (4.1% for R1-resection). CONCLUSIONS: Despite being technically more challenging rsRARP results in a significantly faster recovery of continence and lower number of incontinence pads used. Also, quality of life after a period of three months is significantly higher. Furthermore, rsRARP is associated with a good oncological outcome and a low BCR-rate. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e269-e269 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Joanne Nyarangi-Dix More articles by this author Viktoria Schuetz More articles by this author Maximilian Guettlein More articles by this author David Wuerkner More articles by this author Luisa Hofer More articles by this author Magdalena Goertz More articles by this author Philipp Reimold More articles by this author Katrin Kaltenecker More articles by this author Svenja Dieffenbacher More articles by this author Georgi Tosev More articles by this author Markus Hohenfellner More articles by this author Expand All Advertisement Loading ...