Re-Experiencing Symptoms And Sleep Disturbances In Women With Ptsd

Individuals with post-traumatic stress disorder (PTSD) are at significantly higher risk of developing cardiovascular disease. While there is accumulating evidence that insufficient sleep independently contributes to adverse cardiovascular conditions, the specific associations between PTSD symptoms, cardiovascular variables and sleep disturbances (i.e. disruptive nighttime behaviors) are still unclear. In a group of trauma-exposed civilian women, we assessed the predictive value of the PTSD diagnostic clusters of re-experiencing, arousal and avoidance/numbing on blood pressure (BP), heart rate (HR) and sleep disturbances. We hypothesized that BP, HR and sleep will be differentially linked to specific diagnostic clusters. PTSD status was assessed using the gold-standard clinician administered PTSD scale (CAPS) and PTSD symptom severity via the PTSD Symptom Scale (PSS). We measured baseline BP, HR and quantified sleep disturbances via the Pittsburgh Sleep Quality Index Addendum for PTSD (PSQI-A). Of the 49 women included in the analysis, a subset of 43 (age, 49±12 years old; body mass index (BMI), 37±7 kg/m2) also presented with comorbid depression as per Beck Depression Inventory (BDI). Our analysis yielded no significant correlations between resting BP and CAPS or PSS scores. However, we found a modest correlation between HR and CAPS score (r=.210, p=.074), solely driven by avoidance symptoms (r=.344, p=.009). PSQI-A was correlated with CAPS (r=.536, P