A Mitochondrial-Targeting Iridium(iii) Complex for H2O2-responsive and Oxidative Stress Amplified Two-Photon Photodynamic Therapy

Xinxing Liao,Jinchao Shen,Weijun Wu,Shi Kuang,Mingwei Lin,Johannes Karges,Zilong Tang,Hui Chao

Inorganic chemistry frontiers（2021）

引用 9|浏览15

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摘要

The mitochondrial-targeting iridium(iii) complex Ir–B(OH)2 is activated in the presence of endogenous H2O2 to release the two-photon photosensitizer Ir–OH and the GSH scavenger methylquinone for amplified two-photon photodynamic therapy.

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