When Epilepsy Surgery Becomes The Personalized First-Line Therapy: Is Drug Resistance Really An Inevitable Prerequisite?

National and international guidelines inevitably require the proof of antiseizure drug resistance prior to presurgical diagnostics and especially prior to epilepsy surgery; however, there are individual constellations where epilepsy surgery is not an alternative but the first-line treatment if one considers the risk-benefit ratio. By means of a case report we want to discuss and partly question whether the dogma of antiseizure drug resistance as the prerequisite of epilepsy surgery is always justified.