Palladium-Catalyzed Allylic Cycloaddition Of Vinylethylene Carbonates With 3-Nitrochromone

An efficient method for the enantio- and diastereoselective formation of furanochromanones has been developed via Pd-catalyzed asymmetric allylic cycloaddition of vinylethylene carbonates with 3-nitrochromone. By using a palladium complex generated in situ from [Pd-2(dba)(3)].CHCl3 and phosphoramidite L4 as a catalyst, the transformation allows to rapid access furanochromanones bearing versatile nitro-group and multi-stereocenters in high yields with excellent enantioselectivities and moderate diastereoselectivities.