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143P the Impact of De-Escalation of Adjuvant Systemic Therapy on the Outcome of Women with Early ER+/HER2+ Breast Cancer

V. Jeric Horvat,D. Manevski,M. Pohar Perme,B. Gazic,P. Drev,D. Ribnikar,E. Matos,B. Seruga

Annals of Oncology（2021）

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Abstract
Adjuvant systemic therapy in women with early ER+/HER2+ breast cancer includes chemotherapy (ChT), one year of anti-HER2 therapy and at least five years of hormonal therapy (HT). Here, we explore the impact of de-escalation of adjuvant therapy on the outcome in women with early ER+/HER2+ breast cancer.
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Key words
Neoadjuvant Therapy,Breast Cancer
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