Safety Of Ovarian Preservation In Premenopausal Women With Endometrioid Endometrial Cancer Clinically Confined To The Uterus

Introduction/Background The aims of this study were to determine the frequency of ovarian involvement and to evaluate the impact of ovarian preservation on the recurrence and survival rates in premenopausal women when endometrioid endometrial cancer (EEC) was clinically confined to the uterus. Methodology The medical records of premenopausal women under 50 years-old with EEC surgically treated at our institution between 2004 and 2017 were retrospectively reviewed. Patients were excluded if there were extrauterine diseases on imaging (pelvic MRI and PET-CT) or abnormal intraoperative gross findings around adnexa and/or other sites. Results A total of 144 patients were found to have EEC clinically confined to the uterus, including 79 patients selectively preserving normal appearing ovaries. Ovarian preservation group was younger (p Conclusion Ovarian preservation may be considered in premenopausal women with low-risk endometrioid endometrial cancer clinically confined to the uterus, when there were normal appearing ovaries on preoperative evaluation and intraoperative exploration. Disclosure Nothing to disclose.