Precocious Menarche: Functional Ovarian Cystadenoma?

Precocious menarche is rare and should be investigated when not consistent with pubertal development.Seven-years-old girl with painful bilateral breast button and menarche. Analytically with slightly elevated estradiol, normal endocrinological study and negative tumor markers. Ultrasound showed a large right ovary cystic lesion compatible with an ovarian cystadenoma. Magnetic resonance imaging showed an enlarged right ovary with a medullary cystic lesion and parenchymal preservation, suggestive of an ovarian cystadenoma. Multidisciplinary follow-up showed breast reduction, absence of vaginal hemorrhages or other signs of puberty. One year later, ultrasound showed spontaneous resolution of the ovarian cystadenoma.This case describes a large functional cystadenoma with spontaneous resolution. Non-invasive approach may be safe but clinical close surveillance is imperative.