An Effective Total Synthesis Of Four Angiotensin-Converting Enzymes Containing Silanediols

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY（2021）

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摘要

Four angiotensin-converting enzymes (ACE) containing silanediols 1 have been synthesized successfully in 8% overall yield in 8 steps from inexpensive starting materials such as diphenyldichlorosilane 5, beta-methylallylic alcohol 7 and Ellman sulfinimine 9.

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关键词

Angiotensin-converting enzymes, silandiol, Ellman sulfinimine, diphenyldichlorosilane, beta-methylallylic alcohol, total synthesis

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