Biomarkers of extracellular matrix formation are associated with acute-on-chronic liver failure

JHEP Reports（2021）

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摘要

•Collagen type III and VI formation is increased in ACLF compared to AD.•PRO-C3 and PRO-C6 correlate with the severity of liver dysfunction and inflammation in AD and ACLF.•High PRO-C6 levels were found to be indicative for the presence of multi-organ failure and worse survival.

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关键词

Liver cirrhosis,Multi-organ failure,Collagen,Prognosis

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