Objective:
Evaluating convenient, wearable multi-frequency impedance pneumography (IP)-based respiratory monitoring in ambulatory persons with novel electrode positioning.
Methods:
A wearable multi-frequency IP system was utilized to estimate tidal volume (TV) and respiratory timings in 14 healthy subjects. A 5.1 cm × 5.1 cm tetrapolar electrode array, affixed to the sternum, and a conventional thoracic electrode configuration were employed to measure the respective IP signals, patch and thoracic IP. Data collected during static postures—sitting and supine—and activities—walking and stair-stepping—were evaluated against a simultaneously-obtained spirometer (SP) volume signal.
Results:
Across all measurements, estimated TV obtained from the patch and thoracic IP maintained a Pearson correlation coefficient (
r
) of 0.93
$ \pm $
0.05 and 0.95
$ \pm $
0.05 to the ground truth TV, respectively, with an associated root-mean-square error (RMSE) of 0.177 L and 0.129 L, respectively. Average respiration rates (RRs) were extracted from 30-second segments with mean-absolute-percentage errors (MAPEs) of 0.93% and 0.74% for patch and thoracic IP, respectively. Likewise, average inspiratory and expiratory timings were identified with MAPEs less than 6% and 4.5% for patch and thoracic IP, respectively.
Conclusion:
We demonstrated that patch IP performs comparably to traditional, cumbersome IP configurations. We also present for the first time, to the best of our knowledge, that IP can robustly estimate breath-by-breath TV and respiratory timings during ambulation.
Significance:
This work represents a notable step towards pervasive wearable ambulatory respiratory monitoring via the fusion of a compact chest-worn form factor and multi-frequency IP that can be readily adapted for holistic cardiopulmonary monitoring.
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关键词
Electric Impedance,Humans,Monitoring, Ambulatory,Respiratory Rate,Tidal Volume,Wearable Electronic Devices
