Protective effects of Surfacen® in allergen-induced asthma mice model

Odalys Blanco,Wendy Ramírez,Yuliannis Lugones,Elaine Díaz,Alain Morejón, Valentín S Rodríguez, Wilma Alfonso,Alexis Labrada

International Immunopharmacology（2022）

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摘要

•Surfacen, administered as aerosol, showed a bronchodilator effect comparable to salbutamol.•Surfacen show inhibition of Th2 inflammation (IgE, IL-5 and IL-13 reduction)•Surfacen show inclination towards a Th1 profile (INF-γ and IgG2a antibody responses increased)

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关键词

Pulmonary surfactant,Asthma,House dust mite,Allergy animal model

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