Modeling Innate Antiviral Immunity in Physiological Context

Journal of Molecular Biology（2022）

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摘要

•The innate antiviral immune response is essential for controlling viral infection.•Antiviral responses vary according to species, cell type, and microenvironment.•3D models allow interrogation of antiviral immunity in a physiological context.•Further advancing 3D models will enable additional insight into the host response.

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关键词

pattern recognition receptors,interferon,microenvironment,organoids,tissue engineering

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