Maternal consumption of ɷ3 attenuates metabolic disruption elicited by saturated fatty acids-enriched diet in offspring rats

Debora S Alves-de-Oliveira, Aline M N L G Bloise, Laura M L Silva, Reginaldo L Rocha-Junior, Nelson C Lima-Júnior, Luiza G S Menezes, Elionay G S Silva,Yohanna De Oliveira,Almir G Wanderley, José L de-Brito-Alves, Viviane O N Souza,João H Costa-Silva

Nutrition, Metabolism and Cardiovascular Diseases（2022）

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摘要

•Maternal HFD increased body weight at birth, promoted dyslipidemia, and elevated fasting glucose levels in the HF group.•Maternal ω3 consumption improved birth weight, lipid, glycemic and transaminase biochemical profile of the young offspring.•However, at later adulthood of the offspring, there was no improvement in the biochemical parameters.

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Phenotypic plasticity,High-fat diet,Alpha-linolenic,Transmissible chronic diseases

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