Hyperoside Attenuates Zearalenone-induced spleen injury by suppressing oxidative stress and inhibiting apoptosis in mice

Weifeng Zhu,Ming Ge,Xiuyu Li,Jiangfeng Wang,PanPan Wang,Tiange Tai,Yuxi Wang,Jianxu Sun,Guangliang Shi

International Immunopharmacology（2022）

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摘要

•Hyp protects mice against ZEA-induced spleen injury.•Hyp reduces ZEA-induced spleen injury by inhibiting oxidative stress and apoptosis.•Nrf2 pathway, Bcl-2 family, and caspase pathway play an important role in resisting ZEA-induced spleen injury.

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关键词

Zearalenone,Hyperoside,Nrf2 signaling pathway,Spleen,Oxidative stress,Apoptosis

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