Predictors of Venous Thromboembolism in Patients with Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia

Introduction: The association of malignancy, largely solid tumors, with venous thromboembolism (VTE) is well-known and a widely validated score, Khorana score, guides prophylactic anticoagulation in high-risk patients. However, increasing albeit scarce evidence suggests a high incidence of VTE in patients with hematologic malignancies, which are comparable to high-risk solid tumors. In this study, we sought to explore the incidence and predictors of VTE (including the variables in the Khorana score) in patients with acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) from a large database.