A Multicenter, Prospective Study for Pediatric Chronic Myeloid Leukemia in Chronic Phase: The JPLSG CML-08 Study

Hiroyuki Shimada,Akihiro Watanabe,Masaki Ito,Chikako Tono,Haruko Shima,Yuki Yuza,Hideki Muramatsu,Masahiko Okada,Akihiko Tanizawa

Blood（2021）

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摘要

Background: Tyrosine kinase inhibitor (TKI) has been used in pediatric chronic myeloid leukemia (CML) for more than 10 years, but only a few prospective clinical studies have been conducted in pediatric patients with CML due to their rarity. We conducted the JPLSG CML-08 study to determine the efficacy and tolerability of TKIs in children and adolescents with newly diagnosed CML in chronic phase (CML-CP).

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