P2‐25: Iron Mediates Cigarette Smoke‐induced ACE2 Expression in Bronchial Epithelial Cells

B Conclusions b : Our findings indicated that iron metabolism mediated CS-induced ACE2 expression, suggesting a novel mechanism for increased susceptibility to SARS-CoV-2 infection in smokers. P2-25: Iron mediates cigarette smoke-induced ACE2 expression in bronchial epithelial cells 1 Division of Respiratory Medicine, Nihon University School of Medicine, Japan B Background b : Compared to non-smokers, current smokers were found to be at an increased risk of developing symptomatic coronavirus disease 2019 (COVID-19) owing to their increased airway expression of angiotensin-converting enzyme 2 (ACE2), which is the entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [Extracted from the article] Copyright of Respirology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all Abstracts.)