Title: Revisiting the Stress concept in the context of solid tumors prognostic: a role for the Stress Granules? Running title: Stress granules as novel actors in cancer er progression

Stress Granules formation is a pro-survival mechanism helping cells to cope with environmental challenges. Stress Granules have been studied for two decades in fundamental research, and are now being examined in the context of human pathogenesis. Here, we review studies highlighting stress granules’ involvement in cancer development through translational pattern modification.