Radiologic Management of Lower Gastrointestinal Tract Bleeding

Reference Study Type Patients/ Events Study Objective (Purpose of Study) Study Results Study Quality 1. Dolezal J, Vizda J, Kopacova M. Singlephoton emission computed tomography enhanced Tc-99m-pertechnetate disodium-labelled red blood cell scintigraphy in the localization of small intestine bleeding: a single-centre twelveyear study. Digestion. 2011;84(3):207211. Review/OtherDx 26 patients To present our experience with the detection of bleeding in the small intestine by means of scintigraphy with in vivo-labelled RBCs in the period of 1998-2009. A total of 26 patients had a positive scintigraphy with in vivo-labelled RBCs and 14 patients had negative scintigraphy. The final diagnosis was confirmed in 20/26 patients with a positive scintigraphy by push enteroscopy (6/20), intraoperative enteroscopy (7/20), surgery (4/20), duodenoscopy (1/20), double-balloon enteroscopy (1/20) and X-ray angiography (1/20). The correct location of the bleeding site was identified by RBC scintigraphy in 15/20 (75%) patients with the confirmed source. The locations of the bleeding site identified by scintigraphy and enteroscopy (push, intraoperative) and surgical investigations were highly correlated in patients with a positive scintigraphy within the first 3 hours. 11/20 correctly localized studies and none of the incorrectly localized studies were positive in the dynamic phase of imaging. In 5 patients (all erroneously localized), scintigraphy was positive only at a period longer than 18 hours. 4