Spatially Controlled Glycocalyx Engineering for Growth Factor Patterning in Embryoid Bodies

Matthew R. Naticchia,Logan K. Laubach,honigfort Daniel J.,purcell Sean C.,Kamil Godula

semanticscholar（2020）

引用 5|浏览2

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摘要

Cell surface engineering with synthetic glycomimetic co-receptors for FGF2 was used to establish gradients of stem cells with enhanced FGF2 affinity in embryoid bodies (EBs). Gradient shape was controlled by pre-assembly of glycomimetics into nanoscale vesicles with tunable dimensions and EB penetrance.

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