Cardiorenal Syndrome

Renal and cardiac crosstalk plays an essential role in maintaining physiological homeostasis. Both organ diseases are prevalent and share common risk factors. Impairment in one organ has the potential to affect the other. This interaction is referred to as cardiorenal syndrome, and it is driven by complex neurohumoral and vascular processes. Cardiorenal syndrome refers to a state of either acute or chronic impairment of both renal and cardiac functions. Despite progress in therapeutic interventions, treatment of cardiorenal syndrome remains challenging. In this chapter, we review the current understanding of the pathophysiological mechanisms of cardiorenal syndrome, as well as its management options.