Microvascular rarefaction in patients with cerebrovascular events

Patricia P Wadowski,Christian Schörgenhofer, Thomas Rieder,Sebastian Ertl,Joseph Pultar,Wolfgang Serles,Thomas Sycha,Florian Mayer,Renate Koppensteiner,Thomas Gremmel,Bernd Jilma

Microvascular Research（2022）

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摘要

Capillary density rarefaction and endothelial dysfunction contribute to chronic hypoperfusion and cerebral small vessel disease. Previous animal experiments revealed spatiotemporal microvascular remodeling directing post-stroke brain reorganization. We hypothesized that microcirculatory changes during acute cerebrovascular events could be reflected systemically and visualized sublingually.

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关键词

Sidestream darkfield videomicroscopy,Capillaries,Microcirculation,Stroke,Ischemic stroke,Transient ischemic attack

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