Development and clinical implications of a novel CRISPR-based diagnostic test for pulmonary Aspergillus fumigatus infection

Zhengtu Li,Mingdie Wang,Teng Xu,Yangqing Zhan, Fengyi Chen,Ye Lin,Shaoqiang Li,Jing Cheng,Feng Ye

Journal of Microbiology, Immunology and Infection（2022）

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摘要

The study offers a new validated CRISPR/Cas13a technique for A. fumigatus detection, providing a simple, rapid and affordable test that is ready for application in the diagnosis of A. fumigatus infection.

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Aspergillus fumigatus,Aspergillosis,Diagnosis,CRISPR,PCR

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