Gasdermin Pore Forming Activities that Promote Inflammation from Living and Dead Cells

Journal of Molecular Biology（2022）

引用 6|浏览7

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摘要

•Gasdermins are ancient pore forming proteins.•Gasdermins function as channels for cytokine secretion or mediators of pyroptosis.•Multiple levels of regulation control gasdermin pore forming activities.

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关键词

innate immunity,gasdermin,inflammasomes,IL-1,pyroptosis

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