Association of Family Cancer History With Pathogenic Variants in Specific Breast Cancer Susceptibility Genes.

Allison W Kurian,Paul Abrahamse,Kevin C Ward,Ann S Hamilton,Dennis Deapen,Jonathan S Berek,Lily Hoang,Amal Yussuf,Jill Dolinsky,Krystal Brown,Thomas Slavin,Timothy P Hofer,Steven J Katz

JCO precision oncology（2021）

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摘要

Extent of family cancer history is not differentially associated with PVs across established breast cancer susceptibility genes and cannot be used to personalize genes selected for testing.

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关键词

pathogenic variants,family cancer history,breast cancer,genes

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