An intensive exercise-based training program reduces prefrontal activity during usual walking in patients with Parkinson’s disease

I. Hoang,M. Ranchet, M. Cheminon,R. Derollepot,H. Devos,S. Perrey, J. Luauté, T. Danaila,L. Paire-Ficout

Clinical parkinsonism & related disorders(2022)

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摘要
•Patients with Parkinson’s disease have increased prefrontal activity during usual walking.•After SIROCCO training, prefrontal activity decreased and gait performance improved in patients.•An intensive exercise-based training program increased automaticity of gait in patients with PD.•Findings highlight the potential of neuroplasticity in PD after exercise.
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关键词
Parkinson’s disease,Intensive training program,Physical activity,Usual walking,Prefrontal cortex,fNIRS
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