Combining GCN and Bi-LSTM for Protein Secondary Structure Prediction

Hailong Jin,Wei Du,Jiawei Gu,Tianhao Zhang,Xiaohu Shi

2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)（2021）

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摘要

Protein secondary structure prediction is still a challenging task in bioinformatics, especially for 8-state (Q8) classification. To address this problem, we have proposed a deep learning based model by integrating graph convolutional network(GCN) and bidirectional long short-term memory (Bi-LSTM) network in this paper. In the model, GCN is utilized to synthesize the information of amino acids and...

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关键词

Proteins,Deep learning,Protein engineering,Biological system modeling,Predictive models,Amino acids,Encoding

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