H-VAE: A Hybrid Variational AutoEncoder with Data Augmentation in Predicting CRISPR/Cas9 Off-target

Weiming Xiang,Dong Chen,Yingbo Cui,Shaoliang Peng

2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)（2021）

引用 0|浏览5

暂无评分

摘要

CRISPR/Cas9-based gene editing technology has been widely used in various cells and organisms. However, the off-target effects will bring unpredictable consequences to the organism edited. One of the main obstacles to predict CRISPR/Cas9 off-target is the imbalance of the number of positive and negative samples, which puts forward a challenge for the training of traditional deep learning algorithm...

查看译文

关键词

Training,Deep learning,Codes,Conferences,Prediction algorithms,Organisms,Encoding

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要