Scaling laws and the left main coronary artery bifurcation. A combination of geometric and simulation analyses

•Comparison of in-vivo coronary vessel diameter with existing scaling laws.•Assessment of different power-law criteria in the characterization of blood flow models.•Novel approach to enforce matching between averaged wall shear stresses in branching vessels.•Huo-Kassab’s criterion results in improved shear stress balancing between branching vessels.