Radical cystectomy versus trimodality therapy for muscle-invasive urothelial carcinoma of the bladder

Kenneth Softness,Sumedh Kaul,Aaron Fleishman,Jason Efstathiou,Joaquim Bellmunt,Simon P. Kim,Ruslan Korets,Peter Chang,Andrew Wagner,Aria F. Olumi,Boris Gershman

Urologic Oncology: Seminars and Original Investigations（2022）

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摘要

•Utilized strict criteria to emulate pragmatic target trial.•Compared cystectomy with trimodality therapy for muscle invasive bladder cancer.•Radical cystectomy had similar overall survival to trimodality therapy.•Radical cystectomy has improved survival in clinical T3 disease.

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关键词

Bladder cancer,Radical cystectomy,Radiation therapy,Survival,SPARE,Clinical trial

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