F Plasmid Lineages in Escherichia Coli ST95: Implications for Host Range, Antibiotic Resistance, and Zoonoses.

E. coli ST95 is one of five dominant ExPEC lineages globally and noted for causing urinary tract and bloodstream infections and neonatal meningitis in humans and colibacillosis in poultry. Using high-resolution phylogenomics, we show that F replicon sequence type is linked to ST95 clade structure and zoonotic potential.