Hypophagia induced by salmon calcitonin, but not by amylin, is partially driven by malaise and is mediated by CGRP neurons
Molecular Metabolism(2022)
摘要
•CGRP neurons mediate the effect of the amylin agonist salmon calcitonin (sCT) on food intake.•Amylin's hypophagic effect does not require CGRP neurons.•sCT-induced anorexia but not amylin is associated with malaise.
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关键词
Calcitonin gene-related peptides neurons,Hindbrain,Lateral parabrachial nucleus,Aversion,Emesis,Suncus murinus
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