TREM2-induced activation of microglia contributes to synaptic resilience in non-demented individuals with Alzheimer's neuropathology.

Anna Fracassi,Michela Marcatti,Randy L Woltjer,Giulio Taglialatela

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

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摘要

Our results suggest a higher efficiency of TREM2-induced phagocytic microglia in removing damaged synapses, underlying synaptic resilience in NDAN individuals.

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