The involvement of inflammation in the effect of the administration of donepezil, galantamine, memantine and/or fluoxetine in an animal model of depression and dementia.

Gabriel Casagrande Zabot,Eduarda Behenck Medeiros, Ariandne Oliveira Marques,Bárbara Machado Naspolini Macarini, Adrielly Vargas, Ana Carolina Nunes Colombo, João Behenck,Gustavo De Bem Silveira, Gabriela Serafim Keller,Lisienny Campoli Tono Rempel, Daniel Proença Feijó,Ewa Kucharska,Paulo Cesar Lock Silveira,Gislaine Zilli Réus,Josiane Budni

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

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摘要

The results obtained in the present study indicate that there is a pathophysiological interaction between diseases, and that the association of medications in the future may be a possible therapeutic strategy to reduce the inflammation, especially in association with fluoxetine.

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