Identification of multiple sclerosis-related genes regulated by EBV-encoded microRNAs in B cells

•Epstein–Barr virus (EBV) infection showed the strongest correlation with MS risk.•All MS-related genes in B cells were obtained by integrating MS susceptibility genes and differentially expressed genes.•We investigated the MS-related genes and risk pathways that EBV involved in.•This work identified the target EBV miRNAs and their regulated MS-related genes through bioinformatic prediction and experimental validation.