Critically ill patients with COVID-19 show lung fungal dysbiosis with reduced microbial diversity in patients colonized with Candida spp.

Elisa Viciani,Paolo Gaibani,Andrea Castagnetti,Andrea Liberatore,Michele Bartoletti,Pierluigi Viale,Tiziana Lazzarotto,Simone Ambretti,Russell Lewis,Monica Cricca

International Journal of Infectious Diseases（2022）

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摘要

•Candida spp. colonization was higher in patients with COVID-19 than in those without COVID-19.•• ARDS in COVID-19 was characterized by lung dysbiosis and decreased fungal diversity.•• Ascomycota was more represented in patients with COVID-19 not colonized with Candida spp.

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COVID-19,NGS,Next-generation sequencing,ARDS,Acute respiratory disease syndrome,Dysbiosis,Mycobiome

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