Blood transcriptome profiling identifies 2 candidate endotypes of atopic dermatitis

Lena Möbus,Elke Rodriguez,Inken Harder,Nicole Boraczynski,Silke Szymczak,Matthias Hübenthal,Dora Stölzl,Sascha Gerdes,Andreas Kleinheinz,Susanne Abraham,Annice Heratizadeh,Christiane Handrick,Eva Haufe,Thomas Werfel,Jochen Schmitt,Stephan Weidinger

Journal of Allergy and Clinical Immunology（2022）

引用 11|浏览19

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摘要

AD can be stratified into eosinophilic and noneosinophilic endotypes; such stratification may be useful when assessing stratified trial designs and treatment strategies.

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关键词

Atopic dermatitis,blood transcriptome,RNA-Seq,gene expression,dupilumab,endotypes,eosinophil signatures

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