Safety and humoral response rate of inactivated and mRNA vaccines against SARS-CoV-2 in patients with Multiple Sclerosis

Multiple Sclerosis and Related Disorders(2022)

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摘要
•Information about the humoral response after SARS-CoV-2 inactivated (InV) vaccines in MS is scarce.•178 patients, 123 received InV, 51 mRNA and 4 adenoviral vector vaccines.•Overall positive humoral response was observed in 66.9% (62.6% InV vs. 78.4% mRNA).•Fingolimod patients had 88% positive response, but with lower IgG titres.•AntiCD20 patients had a 43% positive response, related to type of vaccine and number of infusions.
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关键词
Multiple sclerosis,Vaccine,COVID-19,SARS-CoV-2,Humoral response,inactivated virus,mRNA
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