<title>Building an accurate 3D map of prostate cancer using computerized models of 280 whole-mounted radical prostatectomy specimens</title>

In order to develop optimized prostate needle biopsy protocols, we have investigated spatial distribution of prostate tumors using 3D prostate models developed from prostate specimens with localized cancer. An accurate zone- based algorithm has been proposed and developed to calculate a 3D prostate tumor map using 280 reconstructed 3D prostate surface models. Based on the developed 3D tumor map, optimized prostate needle biopsy protocols can be developed. Online guidance can also be provided with the 3D tumor map to the in vivo prostate biopsy of real patients.