Effect of Linezolid plus Bedaquiline against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay

Carolina de Miranda Silva,Amirhossein Hajihosseini,Jenny Myrick,Jocelyn Nole,Arnold Louie,Stephan Schmidt,George L. Drusano

Antimicrobial Agents and Chemotherapy（2018）

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摘要

Tuberculosis is the ninth-leading cause of death worldwide. Treatment success is approximately 80% for susceptible strains and decreases to 30% for extensively resistant strains.

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