Systems Modeling of Cardiomyocyte Mechanobiology

Philip M. Tan, Kyle S. Buchholz,Shulin Cao,Yasser Aboelkassem,Jeffrey H. Omens,Andrew D. McCulloch and Jeffrey J. Saucerman

Molecular & Cellular Biomechanics（2019）

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摘要

In this article, we summarize our systems model of cardiomyocyte mechano-signaling published in PLoS Computational Biology and discuss new approaches to extending these models to predict cardiac myocyte gene expression in response to stretch.

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